You've devoted months--if not years--of your life writing a book. You've sent it off to beta readers, filtered through the feedback, and now you believe you have a polished manuscript. You may have even shopped it around to agents and/or publishers with no bites. Now you wish to self-publish--a movement that has been growing these last few years.
Without thinking, you upload it onto the Amazon KDP and/or Smashwords site, not even bothering to read up on formatting, etc.
Bad, bad move.
Much like the actual writing of the book, take a little time to format it right. I learned this the hard way--almost--when I started formatting Guest of Honor. Let me be up-front on this though. The formatting and preparing can be a pain in the butt.
But it's worth it. Take the time to research and do it right.
Check out a sample even of Guest of Honor, and please give me an honest review of it. Heck, it's only $.99. Less than a bottle of pop, and it'll last a lot longer. I even have a short story added and a sample chapter of Beholder's Eye. Cheap entertainment.